Barcelona are the first team into the quarter-finals on a night when Bayern beat Lyon, Arsenal closed in and Benfica celebrated for the first time.
Defending Champions, Barcelona booked their spot in the last eight with another comfortable win over Hoffenheim.
Before the break, Alexia Putellas converted a penalty after she had been tripped in the area by Laura Wienroither. In the second half, Irene Paredes headed in the second from a corner before Aitana Bonmatí swept home a cross from the excellent Fridolina Rolfö for number three. And the visitors added two more late on, Marta Torrejón nodding in the fourth before Rolfö teed up Ana-Maria Crnogorčević to complete the scoring.
Arsenal moved a step closer to the last eight with a statement win over a stubborn HB Køge.
The Gunners went ahead just past the quarter-hour when Caitlin Foord met Beth Mead’s cross to tap in her second goal in the group. The visitors finally tired in the closing ten minutes and Arsenal pounced, with Lotte Wubben-Moy’s header and a sweet Vivianne Miedema finish sealing the points.
With nine points from four games and two matches to go, Arsenal are second in group C.
In group D, Bayern Munich have brought record winners Olympique Lyon to their knees in the Champions League.
Saki Kumagai, a five-time UEFA Women’s Champions League winner with Lyon, returned to haunt her old club as she headed Bayern to a victory and also made men’s coach Julian Nagelsmann cheer in the stands. The Japanese rose to perfectly meet Carolin Simon’s corner with 21 minutes left and deny OL the point they needed to progress with two games to spare.
Catarina Amado’s dramatic added-time winner gave Benfica a maiden group victory and moved them a point clear of Häcken.
Cloe Lacasse opened the scoring for the Portuguese Champions three minutes into the game before Erlin Rubensson equalised for BK Häcken from the penalty spot in the 74th minute.
But the Portuguese team leapfrogged their hosts in the table after Amado prodded home Francisca Nazareth’s free-kick from close range.