Chelsea forward Romelu Lukaku and Callum James Hudson-Odoi have been ruled out of their Champions League clash against Real Madrid on Tuesday night.

The Blues are set to travel to the Spanish capital for the second leg of their quarter-final tie against the La Liga giants. 

However Thomas Tuchel’s side are 3-1 down on aggregate ahead of the game, with Karim Benzema’s hat-trick last week at Stamford Bridge giving Madrid the advantage.

Speaking to the media ahead of the trip, Thomas Tuchel revealed that both Lukaku and Hudson-Odoi will be absent from the squad through injury.

“Callum Hudson-Odoi out, Ben Chilwell out, Romelu Lukaku will not travel, Azpilicueta has tested negative and is in the group. Ross Barkley is sick.”

Hudson-Odoi has been out of action for the Blues for a few weeks, with the youngster last featuring for the World and European Champions in their FA Cup tie away at Luton Town at the beginning of March.

Chelsea got back to winning ways on Saturday after two defeats at home to Brentford and Madrid. Hammering Southampton 6-0 away from home.

However, Thomas Tuchel’s position on the prospects of defending their European crown hasn’t shifted from his downbeat assessments from midweek, when he said “Our Champions League hopes are over”.

“The result and performance (at Southampton) is good because I am sure that lifts everyone’s spirits,’ Tuchel said.

“But the task is huge. Let’s be honest. Everything is possible in football, but let’s be realistic — it is still the Bernabeu and an opponent very different from today. But it is the best way to prepare.”